Resources
& Links
CANADIAN
EmergentC:
website providing curated
clinical knowledge about COVID-19
Univeristy
Health Network, Toronto, PPE for aerosol generating procedures - YouTube
COVIDCRITICALCARE
Ventilation of COVID : Toronto
Critical Care resources
(Laurent Brochard)
Canadian Anesthesiologists' Society
Intubation
Guidelines for #COVID19
Government of Canada: COVID-19 for
health professionals
Government of Canada: Infection
Preventiona and
Control for COVID-19
Critical
Care Services Ontario: Surge capacity management
Ontario MOHLTC guideance
Public Health Ontario, COVID-19
Pandemic triage, Mike Christian, Crit
Care Clinics,
2019
COVID-19 ICU
intubation procedure (Sinai, Toronto)
INTERNATIONAL
ICS Safety Alert: High
Flow O2 and hospital infrastructure
ISTH Thrombosis in COVID - Webinar
Twitter thread: COVID in
NYC, clinical
charactersitics and management
Ventilating 2 patients on one
ventilator: Columbia
University, March 24th
Surviving Sepsis Guidelines COVID-19
management
synopsis, March 26
ANZICS Guidelines for COVID-19, March
16th
Royal College of Anaesthetists U.K -
COVID-19 resources
SCCM COVID-19 Preparedness Checklist
SCCM
COVID-19 Resources
COVID-19:
National University of Singapore
CDC COVID-19 resources
WHO COVID-19 updates
|
COVID-19
live updates
John Hopkins COVID-19 Global dashboard
WHO COVID19
dashboard
Worldometers COVID-19
COVID-19 in
Ontario, Canada
Ontario
Dashboard (howsmyflattening.ca)
|
COVID-19
in Pregnancy
Outcome of pregnant women with COVID, JAMA Aug 11, 2021
Delivery & oxygenation in COVID, BJOG Aug 10, 2021
COVID vaccination & infection in pregnancy, JAMA
July 12, 2021
COVID pregnancy outcomes: living systematic review,
AOGS Jun 6 2021
Maternal outcomes and risk factors, Sci Rep July 6,
2021
MBRRACE: Learning from COVID maternal deaths in
pregnancy
Preeclampsia and COVID: INTERCOVID longitudinal
study AJOG June26, 2021
Perinatal outcome in Canada, JAMA May 2021
Pregnant women more affected in the second wave?
Lancet May 22, 2021
Mortality of hospitalized pregnant patients with
COVID, Ann Int Med, May 2021
Adverse neonatal outcomes, Swedish cohort, JAMA April
2021
Adverse maternal and neonatal outcome with COVID
(multinational cohort), JAMA
April 22, 2021
Safety of COVID vaccination in pregnancy, NEJM, April
21, 2021
COVID-pregnancy US cohort study, Obstet Gynecol April
2021
UKOSS report (inlcuding B117 variant), March 2021
Pregnancy and immune response to vaccine, March 24 2021
COVID
vaccine in pregnancy information, Ontario PCMCH, Feb 11,2021
Thromboembolic complication of COVID in pregnancy, BMC
Preg Child, Feb 2021
SOGC Statement on vaccination in Pregnancy
(updated Feb 15, 2021)
COVID in pregnancy overview, JAMA Feb 8
COVID Severity & perinatal outcomes, Obstet,
Gynecol Feb 8
Pregnancy, breast-feeding and COVID vaccination, CMAJ,
Jan 27
Clinical characteristics, US cohort study, JAMA Jan 15
ICNARC report, Jan 15 2021
CANCOVID-Preg report, Jan 15 2021
UKOSS prerprint, Jan 5, 2021
RCOG - vaccination in pregnancy & breastfeeding,
Dec 30
ACOG vaccination in pregnancy & lactating mothers,
Dec 21
Canadian surveillance of COVID in pregnancy, AJOG Dec
2020
CANCOVID-Preg report, Dec 2
Rooming-in and breast feeding with COVID+ mothers,
JAMA Dec 7
COVID vaccination in pregnancy, SMFM December 1
Corticosteroids for COVID in pregnancy, Obstet Gynecol
October 2020
COVID & pregnancy outcome from Sweden (increased
preeclampsia), JAMA Sept 23
Pregnancy & COVID: Pharmacological considerations,
Ultras OB Gyn, Sept 21
Pre-procedural asymptomatic COVID, AJOG Sept 21
Clinical manifestation & outcome of COVID in
pregnancy: systematic review, BMJ Sept 1
IH Guideliens: COVID treatment in Pregnancy, Sept 1
High dose Nitric Oxide in pregnant patients with
COVID, Obstet Gynecol Aug 29
MBRRACE UK: Learning from maternal COVID deaths, Aug
2020
ICU admissions of pregnant women with COVID, AJOG Aug
Outcome of pregnant women admitted to ICU with
COVID-19, AJOG Aug 6
Systematic review: maternal & neonatal outcome of
pregnant , hospitalized patints with COVID, IJGO, July 24
Thrombosis and thromboprophylaxis in COVID-19
pregnancy, AOGS, July 17
Including pregnant women in clinical trials of
COVID-19, Ann Int Med, June 29
CDC data on COVID-19 in pregnant women, June 25
Maternal mortality of COVID-19 in pregnant patients
admitted to ICU in NY, Am J Obstet Gynecol, June 15
Systematic
review and meta analysis of COVID-19 in pregnancy, Lancet E-Clinical
Med, June 2020
Prone positioning in pregnancy - an algorithm, Obstet
Gynecol, June 9
COVID in pregnancy in the UK: national cohort study,
BMJ, June 8
Obstetric patients with COVID-19, New York. Obets
Gynecol, May 27
Universal testing of OB patients in NY, AJOG MFM, May
15
Placental pathology in COVID, AJCP May 22
Special supplement, COVID and pregnancy, AJOG, May 2020
Delivery for pregnant women with COVID respiratory
compromise, AJOG, May 23
Case series 46 pregnant women in Washington State,
AJOG May 17
UKOSS report: COVID in pregnancy, May
11
Postpartum exacerbation of COVID,
CMAJ May 6
Maternal death due to COVID, ACOG,
Apr 28
Scoping review of COVID in pregnancy,
Int J Obstet
Gynecol, April 24
COVID in pregnancy: 118 women from
Wuhan, NEJM April 17
Classification of
maternal-fetal-neonatal COVID
disease, AOGS, April 11
Prone positioning in pregnancy, BMC
Preg Childbirth,
2018
Risks of COVID Treatment in pregnancy
Systematic review of maternal
& perinatal
outcomes: 108 patients, AOGS, April 7
Care of pregnant women in labour and
delivery, AJOG
April 10
ACOG Statement: recent developments
with COVID, April 6
COVID-19 in pregnant women: report on
43 pregnant
women from NY, AJOG, April 6
COVID in pregnancy, review, AJOG,
April 5
Perinatal
aspects of COVID-19, J Perinatology, March 26
RCOG: Guide for Maternal Medicine,
March 30
RCOG Q&A's for pregnant
women & COVID,
March 28
RCOG update: March 28
Pregnancy and COVID-19: REVIEW (March
21)
RCOG COVID Maternity eLearning package
COVID in pregnant women (update),
Lancet March 17
Pregnancy & breastfeeding -
CDC, March 17
Anesthetic regimens for Cesarean
delivery - 17
patients, Can J Anesth, March 16
Coronavirus in pregnancy, Obstet
Gynecol March 16th
Royal College of Anaesthetists:
COVID-19 in pregnancy
RCOG: COVID-19 and pregnancy - update
March 13th
CDC Guideline on COVID-19 in
Inpatient Obstetric
settings, March 11
Obstetric Anaesthetists Association
statement on
COVID-19, March 9th
Guidelines for pregnant women with
COVID-19, Lancet March 3 2020
Algorithm
for pregnant women with COVID-19
ACOG
Practice advisory - COVID-19
Coronavirus
Disease 2019
(COVID-19) and Pregnancy:
What obstetricians
need to know. AJOG, Feb 24, 2020
WHO: Clinical management of COVID-19,
Jan 28th
(includes Pediatric & Obstetric patients)
|
Recently
published Literature (see below for "Therapeutics")
Anticoagulation & COVID: Critically ill, NEJM Aug
4, 2021
Anticoagulation & COVID: non-critically ill, NEJM
Aug 4 2021
Recovery after prolonged ICU for COVID, Lancet Aug 1,
2021
PLEX for VITT, NEJM July 7, 2021
Casirivimab and imdevimab RECOVERY trial (preprint),
June 16, 2021
UK guidelines on VITT, 28 May 2021
COVID in African ICU's, Lancet May 22, 2021
ISTH Guidance for managing VITT, April 20, 2021
Mechanisms of VITT (preprint)., April 20th, 2021
Airborne transmission and COVID, Lancet April 15, 2021
TTP after COVID vaccination, NEJM, April 9, 2021
Inhaled budesonide for home tretament, Lancet April 9,
2021
Matched
cohort study (pre/post VOC), BMJ March 10, 2021
RCT ivermectin and COVID, JAMA March 4, 2021
COVID pulmonary physiology (Gattinoni), March 3,
2021
Anticoagulation
in hospitalized patients with COVID-19, Hunt et al, BMJ Feb 19
SOFA for predicting COVID mortality, JAMA Feb 17, 2021
Vit D and COVID, JAMA Feb 17, 2021
Antibody resistance to variants, Preprint, Feb 12, 2021
RECOVERY tocilizumab preprint, Feb 11, 2021
Budesonide and COVID preprint, Feb 8
mRNA vaccine and efficacy against variants, Preprint,
Jan 25
Multiplatform
RCT of full anticoagulation preliminary results, Jan 28
Colchicine in COVID-19 preprint, Jan 27
FICM/ICS Guideline on COVID management, Jan 13 2021
Risk to HCW during COVID intubation, Can J Anesth June
11,2021
REMAP-CAP tocilizumab preprint, Jan 7 2021
Tocilizumab EMPACTA RCT, NEJM Jan 7, 2021
ISARIC4 model for deterioration in COVID, Lancet Resp
Med Jan 11, 2021
-
ISARIC4 online calculator
Canadian surveillance of COVID in pregnancy, AJOG Dec
2020
Baricitinib + remdesivir for COVID, NEJM Dec 11
Risk factors for hospital mortality in US, JAMA Dec 10
Safety and efficicacy of mRNA vaccine, NEJM Dec 10
Risk factors for COVID in cancer patients, JAMA Dec 10
COVID & invasive fungal infections, AJRCCM, Dec 2,
2020
Aspergillosis in COVID, JAMA Dec 8
ARDS phenotypes in COVID-19, Lancet December 2020
Timeline of spectrum of COVID disease, JAMA Nov 18
Cross reacting antibodies in subsaharan Africa, Int J
Infect Dis Nov 7
High prevalence sero-cross + in Africa, Int J Infect
Dis, Nov 2
Virology, tranmission and pathogenesis of COVID-19,
BMJ Oct 23
COVID ARDS Physiology, Intensive Care Med, October 21
SOLIDARITY trial preliminary results, WHO Oct 16
Ivermectin in COVID - retrospective study, Chest Oct 13
Classification of aerosol generating procedures, BMJ,
October 2020
Virology, pathogenesis, transmission of COVID, BMJ,
October
COVID reinfection case report, Lancet Oct 12
Steroids & COVID, Lancet Oct 9
Tracheostomy in COVID, JAMA Oct 8
Remdesivir for COVID, NEJM Oct 8
Long-terms consequences of COVID, JAMA Oct 5
COVID & pregnancy outcome from Sweden (increased
preeclampsia), JAMA Sept 23
Pregnancy & COVID: Pharmacological considerations,
Ultras OB Gyn, Sept 21
Pre-procedural asymptomatic COVID, AJOG Sept 21
COVID & pneumothorax, Europ Resp J, Sept 16
COVID transmission in HCW, Infect Control Hosp
Epidemiol, Sept 9
COVID-19 and mRNA vaccines, JAMA Sept 3
Rapid systematic review: classification of AGMP, BMJ
Aug
JAMA Sept 2 online COVID/steroid publications:
- COVID-19 and steroid therapy - Editorial
- Hydrocortisone RCT
- CODEX dexamethasone RCT
- REMAP-CAP hydrocortisone RCT
- Steroids and COVID-19 metaanalysis
Absence of cytokine storm in COVID-19, JAMA Sept 3
NIH COVID treatment guidelines, Sept 1
Coagulopathy in COVID-19: review , Crit Care Med
Sept
Awake proning: rapid review, J Crit Care Aug 27
COVID-19 in Canada, JAMA Aug 10
Outcome of pregnant women admitted to ICU with
COVID-19, AJOG Aug 6
Convalescent plasma preprint, July 30
Systematic review: maternal & neonatal outcome of
pregnant , hospitalized patints with COVID, IJGO, July 24
Hydroxychloroquine and COVID: Brazilian RCT, NEJM,
July 23
RECOVERY trial: dexamethasone in COVID-19, NEJM July 17
Thrombosis and thromboprophylaxis in COVID-19
pregnancy, AOGS, July 17
Airborne transmission of COVID-19, JAMA July 13
- Twitter thread discussing/refuting above
COVID-19 neurological effects, Brain, July 8
Increased risk of COVID-19 in PPI users, AJG, July 7
Fan et al, COVID-19 ARDS: Lancet Respir Med,
July 6
"Cytokine storm" and COVID-19, JAMA, June 30
Sensitivity of NP swabs and saliva in COVID-19
testing, Clin Inf Dis, June 25
Dexamethasone in COVID-19 (RECOVERY trial) (preprint,
June 22), NEJM July 17
Systematic
review and meta analysis of COVID-19 in pregnancy, Lancet E-Clinical
Med, June 2020
Prone positioning in pregnancy - an algorithm, Obstet
Gynecol, June 9
COVID in pregnancy in the UK: national cohort study,
BMJ, June 8
Chest guidelines on VTED & COVID-19, June 2
Tracheal intubation in patients with COVID-19, CMAJ,
June 1
Period of infectivity with COVID-19, Singapore NCID,
May 23
Delivery for pregnant women with COVID respiratory
compromise, AJOG, May 23
Remdesivir treatment RCT, NEJM, May 22
COVID physiology: respiratory mechanics and gas
exchange (New York), Ann ATS, May 20
Tracheostomy and COVID, Lancet May 15
Prone positioning &
spontaneous breathing (Edit),
JAMA May 15
Physiology of COVID ARDS (Boston),
AJRCCM April 29
Airborne transmission of SARS-CoV-2: narrative review,
Anaestehsia Apr 20
COCHRANE COLLECTION: COVID-19 and
Critical Care
 |
Therapeutics
Budesonide and COVID preprint, Feb 8
Colchicine in COVID-19 preprint, Jan 27
Tocilizumab:
RECOVERY tocilizumab preprint, Feb 11, 2021
REMAP-CAP preprint, Jan 7, 2021
EMPACTA RCT, NEJM Jan 7, 2021
TOCIBRAS (Brazil) BMJ, Jan 20, 2021
BACC
Bay study, NEJM Dec 10, 2020
CORIMUNO study, JAMA Oct 20, 2020
Ivermectin:
Review: clinical and computational, Pharm Reports, Jan
3, 2021
Cohort study, Chest October 12
Systematic review, Pharm Sci, 23 Nov
Steroids & COVID, Lancet Oct 9
Remdesivir for COVID, NEJM Oct 8
Pregnancy & COVID: Pharmacological considerations,
Ultras OB Gyn, Sept 21
JAMA Sept 2 online COVID/steroid publications
- COVID-19 and steroid therapy - Editorial
- Hydrocortisone RCT
- CODEX dexamethasone RCT
- REMAP-CAP hydrocortisone RCT
- Steroids and COVID-19 metaanalysis
High dose Nitric Oxide in pregnant patients with
COVID, Obstet Gynecol Aug 29
Clinical practice guidelines for
COVID management
(Greater Toronto Area), March 30
RECOVERY trial: dexamethasone in COVID-19, NEJM July 17
UK Recovery trial on hydroxychloroquine, online
results June 5
Remdesivir: pharmacology review, Am Col Clin Pharm,
June 2
Managing
drug shortages during COVID, CJ Anesth, May 27
Remdesivir treatment RCT, NEJM, May 22
RCT of interferon, Kaletra, ribavirin
in COVID,
Lancet, May 8
Evidence-based treatment guidelines,
CMAJ, April 29
Remdesevir RCT from China, Lancet
April 29
COVID therapeutic
research updates
Review of pharmacologic treatment of
COVID-19, JAMA,
April 13
Risks of COVID Treatment in pregnancy
Study of compassionate use of
remdesivir, NEJM April 10
Siltuximab (anti-IL-6) study
(Preprint), April 3
Treatment with convalencent plasma -
5 patient, JAMA,
March 27
Lopinovir-Ritonovir RCT, NEJM, March
18
Open label trial of
hydroxychloroquine + azithromycin
(PREPRINT), March 18
Retrospective review of tocilizumab
in COVID-19 in
China (NOT PEER-REVIEWED),
COVID-19: combining antiviral and
anti-inflammatory
treatments, Lancet Feb27, 2020
NIH clinical trial of remdesivir to
treat COVID-19
begins
Hopkins ABX Guide and COVID-19
Coronavirus
puts drug repurposing on the fast track
COVID
drug interactions
Steroids?
Pro - Risk factors associated with ARDS
& mortality,
JAMA March 13th
Con
- Severe SARS-CoV-2 and Intensive Care,
ICM Feb
26th
Research studies
Recombinant Human
Angiotensin-converting Enzyme 2
(rhACE2) as a Treatment for Patients With COVID-19
Study to Evaluate the Safety and
Antiviral Activity of
Remdesivir (GS-5734™) in Participants With Severe COVID-19
The
Efficacy
and Safety of Thalidomide in the Adjuvant Treatment of Moderate New
Coronavirus (COVID-19)
Pneumonia
The
Clinical
Study of Carrimycin v lopinavir/ritonaviron or chloroquine on Treatment
Patients With COVID-19
The
Efficacy of
Intravenous Immunoglobulin Therapy for Severe 2019-nCoV
Infected Pneumonia
RCT of tocilizumab for treatment of
COVID-19 (China)
|
Images,
Infographics,
lists, videos, guidelines
CCSO YouTube channel: COVID management presentations
Position statement of infectivity, Singapore NCID, May
23
Thrombosis UK webinar: Management of thrombosis in
COVID-19, May 19th
Unique attenuating mutation in COVID
Twitter thread on transmission
dynamics, May 4
NHS (England) COVID Guidelines
Protected intubation video (Sinai,
Toronto)
ESICM ventilation webinar (April
2):
- Blog
discussion
- Playback webinar
- Infographic
- Guy's
& St. Thomas Vent algorithm
Mayo Clinic Knowledge Translation for
COVID-19
Stanford
OB Anesthesia intubation & extubation video
ISTH Thrombosis in COVID - Webinar
Hematological managament
of COVID (from Guy's & St. Thomas Hospital)
COVID stages and immune
response
Contained
extubation in a Heliox-filled bag
Using Anesthetic Gas
Machines for ICU ventilation
Calculating
Recruitment/Inflation
ratio & Airway Opening pressure (videos and calculator)
Using Anesthetic Gas
Machines for ICU ventilation
Calculating
Recruitment/Inflation
ratio & Airway Opening pressure (videos and calculator)
"Critical
Care for non-ICU Physicians" - free online by SCCM
Intensive Care Medicine: COVID
simulation guidance,
March 18th
COVID-19 "One Pager" by
Seattle intensivist, Nick Mark
Coping with COVID-19 stress: 3 steps,
By Jon Hunter
& Bob Maunder
Interview by JAMA with Dr. Maurizio
Cecconi from
Lombardy, Italy - March 13th
Advice from OAA - COVI-19
in pregnancy
Algorithm for
pregnant women with
COVID-19
|
Pandemic
Planning
literature
Preparing intensive care for the next
pandemic
influenza, Crit Care 2019
Preparing the ICU for disaster, Crit
Care Clinics 2019
Augmenting critical care capacity in
a disaster, Crit
Care Clin 2019
Triage, Crit Care Clinics, 2019
Disaster Care Considerations in Chronically Ill, Pregnant, and Morbidly
Obese Patients, Crit Care Clin 2019
Chest consensus statement 2014
Critical Care during a Pandemic -
Ontario OHPIP, 2006
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