COVID-19 Critical Care Resources

This website aims to provide reliable up-to-date resources, but with the rapid changes in this situation and the numerous incorrect resources, this cannot always be guaranteed. Older links are archived - see bottom of page

ICU Management of COVID: overviews and guidelines

-  Management Principles of Adult Critically Ill COVID-19 Patients - UoT IDCCM, March 26

- Brigham & Womens's Hospital COVID-19 Critical Care Clinical Guidelines (March 19)

- Massachusetts General Hospital COVID-19 Treatment Guidance, March 17

- Care of the Adult Critically ill COVID-19 Patient: Alberta Health Services
NEW!!

Contained extubation in a Heliox-filled bag

Quick ICU Training for COVID-19 for non-intensivists

Using Anesthetic Gas Machines for ICU ventilation

Calculating Recruitment/Inflation ratio & Airway Opening pressure (videos and calculator)

Canadian Resources & Links


TORONTO COVID-19 - Links & resources

WEEKLY TIPS FROM TORONTO HOSPITALS

EmergentC: website providing curated clinical knowledge about COVID-19

Univeristy Health Network, Toronto, PPE for aerosol generating procedures - YouTube

COVIDCRITICALCARE

Ventilation of COVID : Toronto Critical Care resources (Laurent Brochard)

Canadian Anesthesiologists' Society Intubation Guidelines for #COVID19

Government of Canada: COVID-19 for health professionals

Government of Canada: Infection Preventiona and Control for COVID-19

Critical Care Services Ontario: Surge capacity management

Ontario MOHLTC guideance

Public Health Ontario, COVID-19

Pandemic triage, Mike Christian, Crit Care Clinics, 2019

COVID-19 ICU intubation procedure (Sinai, Toronto)


COVID-19 live updates

John Hopkins COVID-19 Global dashboard
 

WHO COVID19 situation map
WHO map

Worldometers COVID-19

COVID-19 in Ontario, Canada

Financial Times corona virus tracker

International Resources & Links

Surviving Sepsis Guidelines COVID-19 management synopsis, March 26

ANZICS Guidelines for COVID-19, March 16th

Royal College of Anaesthetists U.K - COVID-19 resources

SCCM COVID-19 Preparedness Checklist
SCCM COVID-19 Resources

COVID-19: National University of Singapore

CDC COVID-19 resources
WHO COVID-19 updates
U.K. NHS Guidance on COVID19

WHO: Clinical management of COVID-19, Jan 28th (includes Pediatric & Obstetric patients)

Mass Gen COVID19 Toolkit

Twitter thread: COVID-19 overview, March 4, 2020

Twitter thread on initial COVID-19 research, Jan 25th   (by @mugecevik)
   Thread 2: Updated research thread Feb 9th 2020
    Thread 3: More COVID19 research  March 7 2020

Thread reviewing the Webinar by Dr. Yaseen Arabi: COVID-19 and ICU

Recently published Literature

Cardiac involvement with #COVID-19, JAMA March 27
End of life care for COVID-19 in the Emergency Room, Can J Emerg Med, March 26
Case fatality and characterstics of COVID-19 patients in Italy, JAMA March 23
COVID in pregnant women (update), Lancet March 17
Upper respiratory viral load, NEJM March 18
Aerosol and surface stability of SARS-CoV-2 versus SARS-CoV, NEJM March 18
Lopinavir-Ritonavir trial, NEJM March 18th
Initial USA data, Feb 12- March 16, MMWR March 18
Transmission amongst crew members on cruise ship, MMWR March 17
Lidocaine during intubaiton and extubation of COVID-16, Can J Anaesth, March 16
Case report of fulminant myocarditis treated with steroids & IVIG, Euro H J, March 16
Coronavirus in pregnancy, Obstet Gynecol March 16th
Critical Care utilization in Lomabardy, Italy. JAMA , March 13th
Risk factors associated with ARDS & mortality, JAMA March 13th
Systematic review of studies of clinical aspects of COVID-19, Travel Med Infect Dis, March 13th
Coronvirus in Italy: what next?, Lancet March 13th
Monoclonal antibody against SARS-CoV-2 (PREPRINT), March 12th
Supporting the healthcare workforce during COVID-19, JAMA March 12
Care for Critically ill patients with COVID-19, JAMA March 11th
Detection of  SARS-CoV-2 in clinical specimens, JAMA March 11th
Clinical course & mortality prediction: cohort of 19 pts from China, March 9th
Effect of escalating infection control precautions in Hong Kong, ICHE Journal, March 5
Clinical course of 18 patients from Singapore, JAMA March 3rd, 2020
Critical Care recommendations, Intensive Care Medicine, March 2, 2020
Aerosol dispersion during various respiratory therapies, Hong Kong Med J 2014
COVID-19: challenge for Critical Care, Y. Arabi, Intensive Care Med, March 3, 2020
Surface environmental and PPE contamination by SARS-CoV-2, JAMA March 4, 2020
Severe SARS-CoV-2 and Intensive Care, ICM  Feb 26th
COVID-19 Overview, Jama Feb 28th, 2020

COCHRANE COLLECTION: COVID-19 and Critical Care


             

COVID-19 in Pregnancy

Pregnancy and COVID-19: REVIEW (March 21)
RCOG COVID Maternity eLearning package
COVID in pregnant women (update), Lancet March 17
Pregnancy & breastfeeding - CDC, March 17
Anesthetic regimens for Cesarean delivery - 17 patients, Can J Anesth, March 16
Coronavirus in pregnancy, Obstet Gynecol March 16th
Royal College of Anaesthetists: COVID-19 in pregnancy
RCOG: COVID-19 and pregnancy - update March 13th
CDC Guideline on COVID-19 in Inpatient Obstetric settings, March 11
Obstetric Anaesthetists Association statement on COVID-19, March 9th
Guidelines for pregnant women with COVID-19, Lancet March 3 2020
           Algorithm for pregnant women with COVID-19
ACOG Practice advisory - COVID-19
Coronavirus Disease 2019 (COVID-19) and Pregnancy: What obstetricians need to know. AJOG, Feb 24, 2020
WHO: Clinical management of COVID-19, Jan 28th (includes Pediatric & Obstetric patients)

Images, Infographics, lists, videos

"Critical Care for non-ICU Physicians" - free online by SCCM
Intensive Care Medicine: COVID simulation guidance, March 18th
COVID-19 "One Pager" by Seattle intensivist, Nick Mark
Coping with COVID-19 stress: 3 steps, By Jon Hunter & Bob Maunder
Interview by JAMA with Dr. Maurizio Cecconi from Lombardy, Italy - March 13th
Advice from OAA - COVI-19 in pregnancy
U.K. Donning video    & doffing video
Initial recommendations fom Italy, March 9th
Infographic: initial experience  from Italy: ICUwith COVID-19
Critically ill patients with COVID19
Airway Management - Hong Kong infographic
PPE for COVID19 - Ontario, Canada
Algorithm for pregnant women with COVID-19

Pandemic Planning literature


Preparing intensive care for the next pandemic influenza, Crit Care 2019

Preparing the ICU for disaster, Crit Care Clinics 2019

Augmenting critical care capacity in a disaster, Crit Care Clin 2019

Triage, Crit Care Clinics, 2019

Disaster Care Considerations in Chronically Ill, Pregnant, and Morbidly Obese Patients, Crit Care Clin 2019


Chest consensus statement 2014

Critical Care during a Pandemic - Ontario OHPIP, 2006

Therapeutics

Although there is no data on drug treatment for COVID-19, there are trials underway and rational suggestions from clinicians involved in the care of these patients. These are summarized in the links below.


Treatment with convalencent plasma - 5 patient, JAMA, March 27
Lopinovir-Ritonovir RCT, NEJM, March 18
Open label trial of hydroxychloroquine + azithromycin (PREPRINT), March 18
Retrospective review of tocilizumab in COVID-19 in China (NOT PEER-REVIEWED),
COVID-19: combining antiviral and anti-inflammatory treatments, Lancet Feb27, 2020
NIH clinical trial of remdesivir to treat COVID-19 begins
Hopkins ABX Guide and COVID-19
Coronavirus puts drug repurposing on the fast track
COVID drug interactions

Steroids?
Pro -
Risk factors associated with ARDS & mortality, JAMA March 13th
Con - Severe SARS-CoV-2 and Intensive Care, ICM  Feb 26th

Research studies
Recombinant Human Angiotensin-converting Enzyme 2 (rhACE2) as a Treatment for Patients With COVID-19
Study to Evaluate the Safety and Antiviral Activity of Remdesivir (GS-5734™) in Participants With Severe COVID-19
The Efficacy and Safety of Thalidomide in the Adjuvant Treatment of Moderate New Coronavirus (COVID-19) Pneumonia
The Clinical Study of Carrimycin v lopinavir/ritonaviron or chloroquine on Treatment Patients With COVID-19
The Efficacy of Intravenous Immunoglobulin Therapy for Severe 2019-nCoV Infected Pneumonia
RCT of tocilizumab for treatment of COVID-19 (China)


ARCHIVED LINKS This site developed & maintained by Stephen Lapinsky